Department of Chemistry and Physics

Chemistry

Temporal Dynamics of Caspase Activation in PPI-treated Cancer Cells

by Ashley Utz Faculty Mentor: Professor Randall Reif Cancer cells rely on glycolysis even under normoxic conditions. The use of this pathway results in measurable intracellular acidification, which is characterized as an early event in the apoptosis program. The pH is restored by activation of voltage- gated proton pumps, preventing acidification. Proton pump inhibitors (PPIs), …

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Asymmetric Synthesis of DEHP

By Hannah Harris Faculty Mentor: Professor Davis Oldham Di(2-ethylhexyl) phthalate (DEHP) is a chiral molecule used as a plasticizer in many commercial products, and its metabolites have been linked to endocrine disruption and other adverse health effects in mice. Differences in the toxicity of the enantiomeric forms are not well studied. In order to synthesize …

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Physics

Astronautics: The Physics of Space Flight

By Britteny Backus Faculty Mentor: Professor Varun Makhija Over the course of the semester, my professor and I have collected notes and did research on the book: Astronautics, The Physics of Space Flight. In general, I learned how to apply Newtons laws and the Laws of Thermodynamics to the physics of rockets. Taking simple equations …

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